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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a7264e4a4d1fed6c152ffb9fb86e1156c7742afd001db694cce000385f5ffd2' 
  AND token = 'O5AcVasib/rJ1YrfXdWhpijL+SIVS7y3Y05Ur12uDXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}