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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3c2cdfe2a1a205c5ff3ce9a9421372673ce27c12460d2dce7667de6df835640' 
  AND token = 'g6P5qW03yAjeanN9PYx2thi2cxTjmHCIuCc7L/qt7Cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}