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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccdb1bc3bf50f5657c1faead4e0ece4db88047a64a0923397762d0724b5201fe' 
  AND token = 'vZv2fZD+wZSgOSfPK3B0UyeSEnEwpJbPiqr1BKWLv8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}