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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d8226d3b47876e85737dd3039150f95f0220575ed84801c6872d276887fdc95' 
  AND token = 'tDKz5VRw1LtXXZiZk01m8nt/MZcfOmcPX6Re9vrmZcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}