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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68a5e3f7c1f47efefc78df64185bf1938860773dc2a736c63748a9f160b65c43' 
  AND token = 'U7gwPSm1cy9Pmal45tKHlCR0WiTa63BdTYpNJUSADI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}