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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e58a17dd21ec4f86698e73c7569032a6dd368e3c9a87d704a367904f516d18d0' 
  AND token = 'Cy7fz7D+f4PN6SrrtLiVoLgNC19leW5Vg4wv9YoeSHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}