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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1346e9b39e5392776082c5dc10de4170e9aa617e41cacf312d9c25da0528713a' 
  AND token = 'DjDQdj0Q4QniA3vhzdePGaY657nWUpqUI6wy3apZDh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}