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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f78fdcff07c719c5b28e963c1351a42d56bd096aaf010f05491337b7aae2e46' 
  AND token = 'OvpvqndwLbntnGbcmb4HYkfYo1eKtDf0zgDObpVx20g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}