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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bb7c0040f2af26da787a5df4d03e908d5f7c7661fca7466581b6852961df15f' 
  AND token = 'wufX1vH31BY80F6xwW6G17039bpOxjVEM+rQk5DZaTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}