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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cab94e59e48e3cf7f3c5b942f7f27e5b56d04c506b95d7e6bb874c86aae05d8' 
  AND token = '3zwlkeeSBZdnfhC2RAkXIyiJ3tob24FAIhNPrpxKfuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}