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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d4688c55ef38f49f6452ea9013e4488de9ac3aac1b12af6b9216a9bf357a715' 
  AND token = 'i0Q4oOnsG94PEqkoJ5qHN2UtKdcFn7oG3L6wxB3en44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}