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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa18b493fb87e37281da09ba40af65bbe0b04e1e181702bcd53dffe361f7b24c' 
  AND token = 'UrwSxftkHA3h+wYA2J+YEl2Un33YbURXihTgfKXCsGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}