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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '234b7a452a2f8e03f297ec96411f852a75be11ff9aa3572bf5a48a7f766a1718' 
  AND token = 'E2/v3e/JS978KAsm2a2epuWA9Zu9RM/XMjrM8fHpzOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}