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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fab81c7f21f010cabd65459d4b2e6b7300e8bb6769e679e5456c55b9f802690a' 
  AND token = 'GnAV5b1HsuPOVfyAorHTL3eZnIYAVkL/bDFIkJAT+TY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}