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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '708db8da17602bad162a424d646b82d0d53b116013273c13d7a7f2e611a31faa' 
  AND token = 'aMsn5mLPKHqGkzEiyyDypJ7B9qn+fjAzeYrEx0ISgnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}