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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0095a3c40beccd9c2b935df1e9d781cc1a2c414c1ee322fd387a0c4c8a245234' 
  AND token = 'dFAHioXPuOmWDt21C1hfT8yqlTAf95eTyLUknFSip2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}