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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e67e10dd6c506f488dba60b904315b69deed88f50aecd1d0b44a0f0b15d407c' 
  AND token = 'iglgamHTYvd6ZL46zy21K/RXu6KzdUlsKkxg+Cb80JU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}