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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c7e10b97f30510f247b371d2c31eb0e71a5d8f7723cce0157f74030967e6baa' 
  AND token = 'UT9nhshI+dtFkeyec7ozEjHwKGZ/4MNFQmxjy2kcn9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}