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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48451eae4189adc06f209ddc006fa748fe8f38c689bb1736763aa2ab95d78e3d' 
  AND token = 'XBw0RhGLBWVXxn1Ouipdxqa1XWbpZ1260Rw39blnz44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}