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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '858439857d9ccd69c81b85810e7b3ba7212d878db02360549073c31f33b7495c' 
  AND token = 'vgc6pTRQokjCuK9mHE9ONXZ3EVnnIXVC790aPrV1B6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}