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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ac5e519b9607932b40812638927f9cb6cecfd595aca5ebf752b340713cc4377' 
  AND token = 'j5ustELSL8+IBa666wSQtHHPggPONG9H0yD5yuEn7YY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}