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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5051f3b4c8fad42ed4a9182b444e5cbda3a1511a05aed6c58777b999cc4a1b0d' 
  AND token = '+idN+iaFwRXjc3gLSbUAqhrzd5esnrm2cuTA77fg/AM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}