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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '753d407fd84d0d51167e8bc3940a67b8cac642106e5f9ae787071b607e6f532b' 
  AND token = '8nasQRPop8dTaGP7poDs5+LC2NKPkdzEOvzNIo1KZdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}