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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '568cf4c618d84b8bf6ec61db51c65dbb47e95dec4bff8f214a82db0db68eed6c' 
  AND token = 'UIKxsTYuh2S1pUj4o1YhfxpS+hTrZidiN46XL9tklwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}