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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e4a264db18b54baa26eb4bcea974d0c1b4b6f2e2ce059b55d8a3269455e78ef' 
  AND token = '2U2NoW554PTawy1X5rh/ZCjuR7IUrH+RfUEe06cBXfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}