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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2cf56fda8b8c48b438e4b12b55b86751455d01164bb111f4960e9f3941a19a2' 
  AND token = 'McWiW68hbzd54rCFHEsRk0eGKoB4Gl1sR9o9u/ZCmj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}