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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da4f87ca82fe5533af579c58fffec66fe3aab2e9b75af281c9f3dfdc8b006b6e' 
  AND token = 'l8ZKGTE1PRxU0WQmNIksOZCWiAGgW5P5+ZZq5PLRzyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}