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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a19c9971136e7e4d1ba8063d7144ec5b13f8dbb4812290a0c586c9abda2d812f' 
  AND token = 'M3Zeb19fl35vSoMH0AeICGmrNbAuh0a7E+y8/ovXKI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}