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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd589516b41ce9109ccdb9fd73a381f6666165ec41b89d3f375097e701ef04538' 
  AND token = '5chtdAPzLIFMzuNf4USi6drjh4I/B9ZcwrGbPrELgPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}