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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a860c6788c8b1f0e09dd50926331702ebe918f1f4aaa8e1f7d22b69a3181c7c' 
  AND token = 'R9iQJV1e7JrR0xggZtCCzqG4qzKyvfpBOZsv1+vfCm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}