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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eed4c209c7f007565236694a655f0fffed7d6df1e99c4dab5127d2b24d6fc07e' 
  AND token = 'K0ATh/+Ay2HsY1j6DPejwLeFqP1uZQZcMzIqGiDHt04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}