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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed2ebdeea7b3b476c7c5caa1273b4a8ad3c64f7c4248ab06d47332172a732050' 
  AND token = 'TENt+WCsex3tLkSUkf46SVDoP7wEtJt6ZtZ2gZdtP9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}