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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37843dc1167a6e9637e86bc2aa7eda67aa4638ef6ad1fc182ea001a91ea54846' 
  AND token = 'V3/8IGW2fPt+CF1TxbRqTzuMT63ccvr0nOm7CpDtHA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}