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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77d756d2773c737d2dac5275460e6fc01915e0182a61f34e28d41809ca2f99eb' 
  AND token = '+KespeACU0gutkViAdHMussci0M3bjY6vNfQQq0fDU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}