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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91735ef91bf616736e066effee6284d8ac95d0395479242420b9ffe536f6b108' 
  AND token = 'xgMYjNz2MyD4k8yov5Zf+mvGq5mFX/cFI3Hy49f6KyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}