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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d2e5b21746b92db05e6ab3ffc70a4168019c0df6072e01db41bd4cced921d54' 
  AND token = 'BVWWXPg+/Am1dkEN9p3CW9rEry82lhd0DdkxAZZH2aM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}