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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab12fcbf6a12ea6353819e450f726d403bb1f68ce3196b9708c954a4da211e9f' 
  AND token = 'qxTdWKTw09yB8OchvQQXdNEJiiIZ6R8TXbomx5WbeHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}