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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381d3b8db2823e1215d92e01763e10ffd7b91a3b195a84e6ad8fcb9fb1031204' 
  AND token = 'bXtRamKtVp/FrqabVMNUYIdh+xEYtkyAinqUKfzHo1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}