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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0b834652da91d0c028004ed28fc5bfc60bb9b65a8492c87d2a6cd5860ec5757' 
  AND token = '+vkSrZX72b+Gd4ZexxffTXJpy56AaBApKYCoYnywGQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}