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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b23b2eac745860ff25c3dde3ba10e711761b91690e575a1ecbd81ec31d1a9e0' 
  AND token = 'wyP9BOAlfvt6UW8rkCeXEQT0YvQVnQV9oBrqW/oIouU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}