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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8ec45c39c8076b54ee7f0db58897236133f356c8f09c247b6736e188eb8e960' 
  AND token = 'UsiG5TDSB5SnRh6wtqBMV2M8yJOhxapLP+TUdasZdfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}