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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bb65623eb3d991a5da1a677a249a090263bfe1cd05e61aa188a4562b8fa0c47' 
  AND token = '7/HX5znQ/rQV1KqP7BaaoLInyMaTdWaFSsZLQmsbAnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}