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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '157e376d53f96ff91fb2280c7e6276caf200c61e092a6d0b5baa2c06707d5ff9' 
  AND token = 'nbT4m65Cs8gkyHFoJ/rCDOGM9qzZ7+NhtkQrx1xAnj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}