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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b840411680850adf2cacb518ca9438120c813dafbbf3343ccacb38680cd30c10' 
  AND token = 'C0V2uxuA2qPTu13R20GuMYRvt3zB17Q1cCqeLgIZ9tI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}