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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427bff194d6c268a33a804901023888a28f869327a218ec78f969058e633c71b' 
  AND token = '/9UeJxDt6oZVOuqo8Ls0ty0IOGB+Ze+rwZocjcZr7jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}