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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f25faed68a35f9975496c97e77b7e99091ef2ba218994cab6ade7de89c343fe' 
  AND token = 'iIjY/s7ZtEYnlSkZGx/QZRuD86hUkp/9nU168jn6H8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}