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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '706752b2ebd22f679e33b491ae0b674a0c9407040a2715d884338edad534f079' 
  AND token = 'HLzSE/kxNHNW4HZnu52Toe5cLUBm/zs/6U3Hia+BNls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}