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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c5c0cb9163219e74e9e3f2a9558a0b41a76a2175be57b7b5e10cc6d796ab496' 
  AND token = 'fx+huWSP3GsPnhVSY3Z68pYToHyKiTuI43UokcEplTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}