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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3510a735638b83a47330059d77b7fe45b4486972b200c79181121083cfaa0b43' 
  AND token = '5oPBDdu3tnIFfbuW1w2LuO+cRqJTFxiEV5RIvZ+QXj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}