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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c16a90b3356c5c652fe2fc1a900cafa9f4fcbf4fa314d50d4081b8abefc46ff5' 
  AND token = 'q6wO0tCk7+g4XVJ/qjF6DEYiEjIJ8WLIlt/WoXRUHxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}